Transsphenoidal Surgery for Cushing Disease
نویسندگان
چکیده
منابع مشابه
Transsphenoidal surgery for cushing disease after nondiagnostic inferior petrosal sinus sampling.
BACKGROUND Inferior petrosal sinus sampling (IPSS) is a useful technique for confirming a pituitary source of adrenocorticotropic hormone (ACTH) overproduction in Cushing disease. Uncertainty remains regarding the appropriate course of therapy when an ectopic tumor is predicted by IPSS but none can be found and in circumstances when the procedure cannot be successfully completed owing to techni...
متن کاملLong-term follow-up on Cushing disease patient after transsphenoidal surgery
Cushing disease is caused by excessive adrenocorticotropic hormone (ACTH) production by the pituitary adenoma. Transsphenoidal surgery is its first-line treatment. The incidence of Cushing disease in children and adolescents is so rare that long-term prognoses have yet to be made in most cases. We followed-up on a 16-year-old male Cushing disease patient who presented with rapid weight gain and...
متن کاملUnmasking sarcoidosis following surgery for Cushing disease
We present a patient with Cushing disease apparently suppressing sarcoidosis, which was unmasked following surgical resection of a pituitary adrenocorticotropin (ACTH)-producing microadenoma. Case report and a short review of the literature published in this area. A 46-year-old Caucasian woman presented with symptoms of hypercortisolism such as progressive weight gain, Cushingoid appearance, pr...
متن کاملTranssphenoidal surgery for Cushing's disease: defining cure and following outcome.
Ideally, selective and complete removal of a corticotroph adenoma should cure Cushing's disease and leave no other pituitary dysfunction. Furthermore, endocrinologists should be in a position to inform patients with Cushing's disease whether they are cured following transsphenoidal surgery. As with diagnosis of this condition, however, definition of cure continues to be debated. Such definition...
متن کاملMicroscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents
Background & Aim: We described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms. Methods & Materials/Patients: A total of 21 participants with histologically v...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2011
ISSN: 1524-4040,0148-396X
DOI: 10.1227/neu.0b013e31822dda2c